Research
Our efforts will focus on two areas of application. First is the genetic mapping of loci associated with complex and quantitative traits and the other is the analysis of data from large scale gene expression assays.
These two areas of research hold great promise for discovering the role of genes in determining individual phenotypes. They complement one another and the power of both approaches will be greatly enhanced by the availability of complete genomic sequences.
It remains a challenging and open problem to understand how the simultaneous action and interaction of multiple genes determines a complex phenotypic state. Statistical and computational tools are needed for both the experimental design and interpretation of data resulting from the application of these technologies.
Because theoretical tools are best developed in the context of real problems, we have recently become involved in experimental work and plan to continue to expand the role of experimental investigation as part of our research program.
