VI.C. Treatment data

Many of our studies have tested hypotheses of treatments proposed to delay aging and senescence. Following is data from some of these studies.

Activated lipid (HDL and LDL)

Table VI.9.

Figure VI.6.
Figure VI.7.
Figure VI.8.
Table VI.10

C57BL/6J males and B6CBAT6F1 females: changes in weight among activated lipid fed, control, and colony control mice.
B6CBAT6F1 females: life span curves for activated lipid fed and control mice.
Young mice (30 to 210 days): weight comparisons among lipid fed, control, and colony control mice.
Old mice (860 to 963 days): weight comparisons among lipid fed, control, and colony control mice.
Biomarker values for young and old mice compared to controls.

 Chromium picolinate

Figure VI.9.
Figure VI.10.
Figure VI.11.
Figure VI.12.

Life span curves: treated vs. controls.
Food consumption: comparisons between treated mice and untreated controls.
Weight: comparisons between treated mice and untreated controls.
Tail length: comparisons between treated mice and untreated controls.

 Distilled water

Figure VI.13.
Figure VI.14.
Figure VI.15.

C57BL/6J males and females: combined life spans of treated and untreated mice.
C57BL/6J males and females: weight comparisons of treated and untreated mice.
C57BL/6J males and females: tail length comparisons of treated and untreated mice.

 Exercise

Figure VI.16.

Effects of voluntary wheel running on life span.

Diet restriction

Diet restriction is so widely recognized as a treatment to delay aging that we now use diet restricted animals as controls in many of our aging studies. Data from our diet restriction studies is currently not available on this website. For information, please contact Dr. Harrison at david.harrison@jax.org.

  • C57BL/6J males and diet restriction
  • C57BL/6J females and diet restriction
  • Obesity and diet restriction
  • "On-a-day" — "off-a-day" diet restriction
  • Ain766 and diet restriction
  • Knapka diet and diet restriction
  • Diallele cross, with affects of diet restriction on life span and reproduction

Other treatments

Data for the following treatment studies is currently unavilable on this webise. For information, please contact Dr. Harrison at david.harrison@jax.org.

  • Dwarf mutation
  • "little" mutation
  • Deprenyl
  • Hypophysectomy
  • DHEA sulfate
  • Trisomic mutation (Down syndrome model)

Back to Available data contents page

Back to Gerontology home

Site last updated September 13, 2008.