Harrison publications
Following are lists of journal publications and books, book chapters, and reviews authored by Dr. Harrison.
Journal publications:
Strong R, Miller RA, Astle CM, Floyd RA, Flurkey K, Hensley KL, Javors MA, Leeuwenburgh C, Nelson JF, Ongini E, Nadon NL, Warner HR, Harrison DE. 200_. Nordihydroguaiaretic acid and aspirin increase lifespan of genetically heterogeneous male mice. Aging Cell. (Epub ahead of print)
Nadon NL, Strong R, Miller RA, Nelson J, Javors M, Sharp ZD, Peralba JM, Harrison DE. 2008. Design of Aging Intervention Studies: the NIA Interventions Testing Program. AGE online. April 18, 2008.
Brooks NL, Trent CM, Raetzsch CF, Flurkey K, Boysen G, Perfetti MT, Jeong Y-C, Klebanov S, Patel KB, Khodush VR, Kupper LL, Carling D, Swenberg JA, Harrison DE, Combs TP. 2007. Low utilization of circulating glucose after food withdrawal in Snell dwarf mice. J Biol Chem. 282(48):35069-35077.
Ertl RP, Chen J, Astle CM, Duffy TM, Harrison DE. 2007. Effects of dietary restriction on hematopoietic stem cell aging are genetically regulated. BLOOD. Oct 19 111(3):1709-1716.
Flurkey K, Brandvain Y, Klebanov S, Austad SN, Miller RA, Yuan R, Harrison DE. 2007. PohnB6F1: a cross of wild and domestic mice that is a new model of extended female reproductive life span. J Gerontol A Biol Sci Med Sci. 62:1187-1198.
Miller RA, Harrison DE, Astle CM, Floyd RA, Flurkey K, Hensley KL, Javors MA, Leeuwenburgh C, Nelson JF, Ongini E, Nadon NL, Warner HR, Strong R. 2007. An aging interventions testing program: study design and interim report. Aging Cell. 6:565-575.
Sharma Y, Astle CM, Harrison DE. 2007. Heterozygous Kit mutants with little or no apparent anemia exhibit large defects in overall hematopoietic stem cell function. Exp Hematol. 35:214-220.
Powers RW III, Harrison DE, Flurkey K. 2006. Pituitary removal in adult mice increases life span. Mech Ageing Dev. 127:658-659.
Yuan R, Flurkey K, Van Aelst-Bouma R, Zhang W, King B, Austad S, Miller RA, Harrison DE. 2006. Altered growth characteristics of skin fibroblasts from wild-derived mice, and genetic loci regulating fibroblast clone size. Aging Cell. 5:203-212.
Klebanov S, Astle CM, DeSimone O, Ablamunits V, Harrison DE. 2005. Adipose tissue transplantation protects ob/ob mice from obesity, normalizes insulin sensitivity and restores fertility. J Endocrinol. 186:203-211.
Papaconstantinou J, Deford JH, Gerstner A, Hsieh CC, Boylston WH, Guigeaux MM, Flurkey K, Harrison DE. 2005. Hepatic gene and protein expression of primary components of the IGF-1 axis in long lived Snell dwarf mice. Mech Ageing Dev. 126(6-7):692-704.
Sharma Y, Flurkey K, Astle CM, Harrison DE. 2005. Mice severely deficient in growth hormone have normal hematopoiesis. Exp Hematol. 33:776-783.
Yuan R, Astle CM, Chen J, Harrison DE. 2005. Genetic regulation of hematopoietic stem cell exhaustion during development and growth. Exp Hematol. 33:243-250.
Boylston WH, Gerstner A, DeFord JH, Madsen M, Flurkey K, Harrison DE, Papaconstantinou J. 2004. Altered cholesterologenic and lipogenic transcriptional profile in livers of aging Snell dwarf (Pit1dw/dwJ) mice. Aging Cell. 3(5):283-296.
Warner H, Anderson J, Austad S, Bergamini E, Bredesen D, Butler R, Carnes BA, Clark BF, Cristofalo V, Faulkner J, Guarente L, Harrison DE, Kirkwood T, Lithgow G, Martin G, Masoro E, Melov S, Miller RA, Olshansky SJ, Partridge L, Pereira-Smith O, Perls T, Richardson A, Smith J, von Zglinicki T, Wang E, Wei JY, Williams TF. 2005. Science fact and the SENS agenda. What can we reasonably expect from ageing research? EMBO Rep. 6:1006-1008.
Madsen MA, Hsieh CC, Boylston WH, Flurkey K, Harrison DE, Papaconstantinou J. 2004. Altered oxidative stress response of the long-lived Snell dwarf mouse. Biochem Biophys Res Comm. 318:998-1005.
Chen J, Astle CM, Harrison DE. 2003. Hematopoietic senescence is postponed and hematopoietic stem cell function is enhanced by dietary restriction. Exp Hematol. 31(11):1097-1103.
Chen J, Astle CM, Harrison DE. 2003. Hematopoietic stem cell functional failure in interleukin-2 deficient mice. J Hematother Stem Cell Res. 11(6):905-912.
TeKippe M, Harrison DE, Chen J. 2003. Expansion of hematopoietic stem cell phenotype and activity in Trp53-null mice. Exp Hematol. 31(6):521-527.
Chen J, Astle CM, Harrison DE. 2002. Hematopoietic stem cell functional failure in interleukin-2-deficient mice. J Hematother Stem Cell Res. 11(6):905-912.
Chen J, Flurkey K, Harrison DE. 2002. A reduced peripheral blood CD4+ lymphocyte proportion is a consistent aging phenotype. Mech Ageing and Dev. 123:145-153.
Chen J, Harrison DE. 2002. Quantitative trait loci regulating relative lymphocyte proportions in mouse peripheral blood. Blood. 99(2):561-566.
Flurkey K, Papaconstantinou J, Harrison DE. 2002. The Snell dwarf mutation Pit 1(dw) can increase life span in mice. Mech Ageing Dev. 123:121-130.
Hsieh CC, DeFord JH, Flurkey K, Harrison DE, Papaconstantinou J. 2002. Implications for the insulin signaling pathway in Snell dwarf mouse longevity: a similarity with the C. elegans longevity paradigm. Mech Ageing Dev. 123:1229-1244.
Hsieh CC, DeFord JH, Flurkey K, Harrison DE, Papaconstantinou J. 2002. Effects of the Pit 1 mutation on the insulin signaling pathway: implications on the longevity of the long-lived Snell dwarf mouse. Mech Ageing Dev. 123:1245-1255.
Klebanov SE, Harrison DE. 2002. Optimizing detection of QTLs retarding aging: choice of statistical model and animal requirements. Mech Ageing Dev. 123:131-144.
Taylor PA, McElmurry RT, Lees CJ, Harrison DE, Blazar BR. 2002. Allogenic fetal liver cells have a distinct competitive engraftment advantage over adult bone marrow cells when infused into fetal as compared with adult severe combined immunodeficient (scid) recipients. Blood. 99(5):1870-1872.
Allison DB, Miller RA, Austad SN, Bouchard C, Leibel R, Klebanov S, Johnson T, Harrison DE. 2001. Genetic variability in responses to caloric restriction in animals and in regulation of metabolism and obesity in humans. J Gerontol. Series A 56A (Spec Iss 1):55-65.
Flurkey K, Papaconstantinou J, Miller RA, Harrison, DE. 2001. Lifespan extension and delayed immune and collagen aging in mutant mice with defects in growth hormone production. Proc Natl Acad Sci USA. 98:6736-6741.
Klebanov SE, Astle CM, Roderick TH, Flurkey K, Archer JR, Chen J, Harrison DE. 2001. Maximum life spans in mice are extended by wild strain alleles. Exp Biol Med. 226(9):854-859.
Klebanov SE, Flurkey K, Roderick TH, Archer JR, Astle CM, Chen J, Harrison DE. 2001. Heritability of life span in mice and its implication for direct and indirect selection for longevity. Genetica. 110:209-218.
Abkowitz JL, Golinelli D, Harrison DE, Guttorp P. 2000. In vivo kinetics of murine hemopoietic stem cells. Blood. 96(10):3399-3405.
Chen J, Astle CM, Harrison DE. 2000. Genetic regulation of primitive hematopoietic stem cell senescence. Exp Hematol. 28:442-450.
Chen J, Astle CM, Muller-Sieburg CE, Harrison DE. 2000. Primitive hemopoietic stem cell function in vivo is uniquely high in the CXB-12 mouse strain. Blood. 96(13):4124-4131.
Zhao Y, Lin Y, Zhn G, Louie J, Harrison DE, Anderson WF. 2000. Murine hematopoietic stem cell characterization and its regulation in BM transplantation. Blood. 96(9):3016-3022.
Chen J, Astle CM, Harrison DE. 1999. Development and aging of primitive hematopoietic stem cells in BALB/cBy mice. Exp Hematol. 27:928-935.
Chen J, Astle CM, Harrison DE. 1998. Delayed immune aging in diet-restricted B6CBAT6 F1 mice is associated with preservation of naive T cells. J Gerontol. 53A:B330-337.
Gardner RV, Astle CM, Harrison DE. 1997. Hematopoietic precursor cell exhaustion is a cause of proliferative defect in primitive hematopoietic stem cells (PHSC) after chemotherapy. Exp Hematol. 25:495-501.
Harrison DE. 1997. Animal models showing "accelerated aging" are more likely to be useful for pathology than mechanisms of aging. Growth Dev Aging. 61:167-8.
Harrison DE, Astle CM. 1997. Short- and long- term multilineage repopulating hemopoietic stem cells in late fetal and newborn mice; models for human umbilical cord blood. Blood. 90:174-81.
Harrison DE, Roderick TH. 1997. Selection for maximum longevity in mice, and other mouse models for aging research. Kyoto Course on Animal Models for Aging Research. Exp Gerontol. 32:65-78.
Harrison DE, Zhong RK, Jordan CT, Lemischka IR, Astle CM. 1997. Relative to adult marrow, fetal liver repopulates nearly 5 times more effectively over the long-term than short-term. Exp Hematol. 25:293-7.
Archer JR, Harrison DE. 1996. L-deprenyl treatment in aged mice slightly increases lifespans, and greatly reduces fecundity by aged males. J Gerontol Biol Sci. 51A:B448-53.
Zhong RK, Astle CM, Harrison DE. 1996. Distinct developmental patterns of short-term and long-term functioning lymphoid and myeloid precursors defined by limiting dilution analysis in vivo. J Immunol. 157:138-45.
Zhong RK, Donnenberg AD, Edison L, Harrison DE. 1996. The appearance of Thy-1 negative donor T-cells in the peripheral circulation 3-6 weeks after bone marrow transplantation (BMT) suggests an extrathymic origin. Internat Immunol. 8:171-6.
Harrison DE, Roderick TH, Paigen K. 1995. Allele capture by selection for flanking markers: a new method for analyzing multigenic traits. Growth Dev Aging. 59:73-6.
Jordan CT, Astle CM, Zawadski J, Mackarenhtschian K, Lemischka IR, Harrison DE. 1995. Long term repopulating abilities of enriched fetal liver stem cells measured by competitive repopulation. Exp Hematol. 23:1011-15.
Willott JF, Erway LC, Archer JR, Harrison DE. 1995. Genetics of age-related hearing loss in mice. II. Strain differences and effects of caloric restriction on cochlear pathology and evoked response thresholds. Hear Res. 88:143-155.
Harrison DE. 1994. Potential misinterpretations using models of accelerated aging (guest editorial). J Gerontol. 49:B245.
Biossonneault GA, Harrison DE. 1994. Obesity minimizes the immunopotentiation of food restriction in ob/ob mice. J Nutr. 124:1639-46.
Harrison DE, Zsebo KM, Astle CM. 1994. Splenic primitive hematopoietic stem cell (PHSC) activity is enhanced by steel factor because of PHSC proliferation. Blood. 83:3146-51.
Bronson RT, Lipman RD, Harrison DE. 1993. Age-related gliosis in the white matter of mice. Brain Res. 609:124-8.
Erway LC, Willott JF, Archer JR, Harrison DE. 1993. Genetics of age-related hearing loss in mice. I: Inbred and F1 hybrid strains. Hear Res. 65:125-32.
Gardner RV, Lerner C, Astle CM, Harrison DE. 1993. Assessing permanent damage to primitive hematopoietic stem cells (PHSC) after chemotherapy using the competitive repopulation assay. Canc Chemother & Pharm. 32:450-4.
Harrison DE, Jordan CT, Zhong RK, Astle CM. 1993. Primitive hemopoietic stem cells: direct assay of most productive populations by competitive repopulation with simple binomial, correlation and covariance calculations. Exp Hematol. 21:206-19.
Lipman RD, Gaillard ET, Harrison DE, Bronson RT. 1993. Husbandry factors and the prevalence of age-related amyloidosis in mice. Lab Anim Sci. 43:439-44.
Flurkey K, Miller RA, Harrison DE. 1992. Cellular determinants of age-related decrements in the T-cell mitogen response of B6CBAF1 mice. J Gerontol. 47:B115-20.
Harrison DE, Zhong RK. 1992. The same exhaustible multilineage precursor produces both myeloid and lymphoid cells as early as 3-4 weeks after marrow transplantation. Proc Nat Acad Sci USA. 89:10134-8.
Lerner SP, Anderson CP, Harrison DE, Walford RL, Finch CE. 1992. Polygenic influences on the length of oestrous cycles in inbred mice involve MHC alleles. Euro J Immunogenet. 19:361-71.
Harrison, D. 1991. Last-resort medicine: could it have saved my father? Longevity. (April) 78-9.
Harrison DE, Astle CM. 1991. Lymphoid and erythroid repopulation in B6W-anemic mice: a new unirradiated recipient. Exp Hematol. 19:374-7.
Harrison DE, Lerner C. 1991. Most primitive hematopoietic stem cells are stimulated to cycle rapidly after treatment with 5-fluorouracil. Blood. 78:1237-40.
Harrison DE, Stone M, Astle CM. 1990. Effects of transplantation on the primitive immunohematopoietic stem cell (PSC). J Exp Med. 172:431-437.
Hurbain-Kosmath I, Berault A, Noel N, Polkowska J, Bohin A, Jutisz M, Leiter EH, Beamer WG, Bedigian HG, Davisson MT, Harrison DE. 1990. Gonadotropes in a novel rat pituitary tumor cell line, RC-4B/C. Establishment and partial characterization of the cell line. In Vitro Cell Dev Biol. 26:431-440.
Lerner CP, Harrison DE. 1990. 5-Fluorouracil spares hemopoietic stem cells responsible for long-term repopulation. Exp Hematol. 18:114-118.
Sprecher E, Becker Y, Kraal G, Hall E, Harrison D, Shultz LD. 1990. Effect of aging on epidermal dendritic cell populations in C57BL/6J mice. J Invest Dermatol. 94:247-53.
Stone M, Harrison DE. 1990. A stratified binomial marker model for bone-marrow repopulation experiments. J Theoret Biol. 144:267-273.
Harrison DE, Archer JR. 1989. Natural selection for extended longevity from food restriction (editorial). Growth Dev Aging. 53:3-6.
Harrison DE, Astle CM, Stone M. 1989. Numbers and functions of transplantable primitive immunohematopoietic stem cells. Effects of age. J Immunol. 142:3833-40.
Gardner RV, Astle CM, Harrison DE. 1988. The decrease in long-term marrow repopulating capacity seen after transplantation is not the result of irradiation-induced stromal injury. Exp Hematol. 16:49-54.
Harrison DE, Archer JR. 1988. Biomarkers of aging: Tissue markers. Future research needs, strategies, directions and priorities. Exp Gerontol. 23:309-25.
Harrison DE, Astle CM, DeLaittre J. 1988. Effects of transplantation and age on immunohemopoietic cell growth in the splenic microenvironment. Exp Hematol. 16:213-216.
Harrison DE, Astle CM, Lerner C. 1988. Number and continuous proliferative pattern of transplanted primitive immunohematopoietic stem cells. Proc Natl Acad Sci USA. 85:822-826.
Leiter EH, Premdas F, Harrison DE, Lipson LG. 1988. Aging and glucose homeostasis in C57BL/6J male mice. FASEB. 2:2907-2911.
Harrison DE. 1987. A semiquantitative measure of immune responses against erythropoietic stem cell antigens. Immunogenetics. 26:123-9.
Anklesaria P, Klassen V, Sakakeeny MA, FitzGerald TJ, Harrison D, Rybau ME, Greenberger JS. 1987. Biological characterization of cloned permanent stromal cell lines from anemic Sl/Sld mice and +/+ littermates. Exp Hematol. 15:636-44.
Harrison DE, Archer JR. 1987. Genetic differences in effects of food restriction on aging in mice. J Nutr. 117:376-382.
Harrison DE, Lerner C, Hoppe P, Carlson GA, Alling D. 1987. Large numbers of primitive stem cells are active simultaneously in aggregated embryo chimeric mice. Blood. 69:773-777.
Harrison DE, Lerner CP, Spooncer E. 1987. Erythropoietic repopulating ability of stem cells from long-term marrow culture. Blood. 69:1021-1025.
Danis M, Harrison DE, Thurman RG. 1985. Effect of aging on oxidative metabolism and conjugation in perfused livers of an inbred strain of mice: A pilot study. Age. 8:3-8.
Miller RA, Harrison DE. 1985. Delayed reduction in T cell precursor frequencies accompanies diet-induced lifespan extension. J Immunol. 134:1426-9.
Harrison DE. 1984. Do hemopoietic stem cells age? Monogr Dev Biol. 17:21-41.
Astle CM, Harrison DE. 1984. Effects of marrow donor and recipient age on immune responses. J Immunol. 132:673-7.
Harrison DE, Archer JR, Astle CM. 1984. Effects of food restriction on aging: separation of food intake and adiposity. Proc Natl Acad Sci USA. 81:1835-8.
Harrison DE, Astle CM, Lerner C. 1984. Ultimate erythropoietic repopulating abilities of fetal, young adult, and old adult cells compared using repeated irradiation. J Exp Med. 160:759-71.
Harrison DE, Mobraaten LE. 1984. Skin graft rejection in mice repopulated with marrow of the skin donor type: a Skn gene in a congenic line. Immunogenetics. 19:503-9.
Landreth KS, Kincade PW, Lee G, Harrison DE. 1984. B lymphocyte precursors in embryonic and adult W anemic mice. J Immunol. 132:2724-9.
Harrison DE. 1983. Long-term erythropoietic repopulating ability of old, young, and fetal stem cells. J Exp Med. 157:1496-504.
Harrison DE, Archer JR. 1983. Physiological assays for biological age in mice: relationship of collagen, renal function, and longevity. Exp Aging Res. 9:245-51.
Harrison DE, Carlson GA. 1983. Effects of the beige mutation and irradiation on natural resistance to marrow grafts. J Immunol. 130:484-9.
Legraverend C, Harrison DE, Ruscetti FW, Nebert DW. 1983. Bone marrow toxicity induced by oral benzo(a)pyrene: protection resides at the level of the intestine and liver. Toxicol Appl Pharmacol. 70:390-401.
Wilson MC, Harrison DE. 1983. Decline in male mouse pheromone with age. Biol Reprod. 29:81-6.
Harrison DE. 1982. Must we grow old? Biology Digest. 8:11-25.
Hackbarth H, Harrison DE. 1982. Changes with age in renal function and morphology in C57BL/6, CBA/HT6, and B6CBAF1 mice. J Gerontol. 37:540-7.
Harrison DE, Archer JR, Astle CM. 1982. The effect of hypophysectomy on thymic aging in mice. J Immunol. 129:2673-7.
Harrison DE, Astle CM. 1982. Loss of stem cell repopulating ability upon transplantation. Effects of donor age, cell number, and transplantation procedure. J Exp Med. 156:1767-79.
Ingram DK, Archer JR, Harrison DE, Reynolds MA. 1982. Physiological and behavioral correlates of lifespan in aged C57BL/6J mice. Exp Gerontol. 17:295-303.
Harrison DE. 1981. F1 hybrid resistance: long-term systemic effects sensitive to irradiation and age. Immunogenetics. 13:177-87.
Harrison DE. 1980. Competitive repopulation: a new assay for long-term stem cell functional capacity. Blood. 55:77-81.
Harrison DE. 1980. Lifespans of immunohemopoietic stem cell lines. Adv Pathobiol. 7:187-99.
Harrison DE. 1979. Proliferative capacity of erythropoietic stem cell lines and aging: an overview. Mech Ageing Dev. 9:409-26.
Harrison DE. 1979. Mouse erythropoietic stem cell lines function normally 100 months: loss related to number of transplantations. Mech Ageing Dev. 9:427-33.
Harrison DE, Astle CM, DeLaittre JA. 1979. Processing by the thymus is not required for cells that cure and populate W/WV recipients. Blood. 54:1152-7.
Harrison DE. 1978. Genetically defined animals valuable in testing aging of erythroid and lymphoid stem cells and microenvironments. Birth Defects. 14:187-96.
Harrison DE, Archer JR. 1978. Measurement of changes in mouse tail collagen with age: temperature dependence and procedural details. Exp Gerontol. 13:75-82.
Harrison DE, Archer JR, Sacher GA, Boyce FM. 1978. Tail collagen aging in mice of thirteen different genotypes and two species: relationship to biological age. Exp Gerontol. 13:63-73.
Harrison DE, Astle CM, Delaittre JA. 1978. Loss of proliferative capacity in immunohemopoietic stem cells caused by serial transplantation rather than aging. J Exp Med. 147:1526-31.
Harrison DE, Astle CM, Doubleday JW. 1977. Cell lines from old immunodeficient donors give normal responses in young recipients. J Immunol. 118:1223-7.
Harrison DE. 1976. Avoidance of graft versus host reactions in cured W-anemic mice. Transplantation. 22:47-51.
Astle CM, Harrison DE. 1976. Mitogen synergism in low-responding CBA/CaJ mice. Cell Immunol. 21:192-197.
Harrison DE, Astle CM. 1976. Population of lymphoid tissues in cured W-anemic mice by donor cells. Transplantation. 22:42-6.
Harrison DE, Doubleday JW. 1976. Marrow allograft success with W/Wv anemic mice: relation to skin graft survival times. Immunogenetics. 3:289-97.
Harrison DE. 1975. Normal function of transplanted marrow cell lines from aged mice. J Gerontol. 30:279-85.
Harrison DE. 1975. Defective erythropoietic responses of aged mice not improved by young marrow. J Gerontol. 30:286-8.
Harrison DE, Cherry M. 1975. Survival of marrow allografts in W/Wv anemic mice: effect of disparity at the Ea-2 locus. Immunogenetics. 2:219-29.
Harrison DE, Doubleday JW. 1975. Normal function of immunologic stem cells from aged mice. J Immunol. 114:1314-7.
Harrison DE, Malathi VG, Silber R. 1975. Elevated erythrocyte nucleoside deaminase levels in genetically anemic W/Wv and Sl/Sld mice. Blood Cells. 1:605-14.
Harrison DE. 1973. Normal production of erythrocytes by mouse marrow continuous for 73 months. Proc Natl Acad Sci USA. 70:3184-8.
Murphy ED, Harrison DE, Roths JB. 1973. Giant granules of beige mice. A quantitative marker for granulocytes in bone marrow transplantation. Transplantation. 15:526-30.
Harrison DE. 1972. Lifesparing ability (in lethally irradiated mice) of W/Wv mouse marrow with no macroscopic colonies. Radiat Res. 52:553-63.
Harrison DE. 1972. Marrow transplantation and iron therapy in mouse hereditary microcytic anemia. Blood. 40:893-901.
Harrison DE. 1972. Normal function of transplanted mouse erythrocyte precursors for 21 months beyond donor life spans. Nature (New Biol). 237:220-2.
Harrison DE, Russell ES. 1972. Fetal liver erythropoiesis and yolk sac cells. Science. 177:187.
Harrison DE, Russell ES. 1972. The response of W/Wv and Sl/Sld anaemic mice to haemopoietic stimuli. Br J Haematol. 22:155-68.
Harrison DE, Weissberger E, Taube H. 1968. Binuclear ion containing nitrogen as a bridging group. Science. 159:320-2.
Harrison DE, Taube H. 1967. The formation of Ru(NH3)5 N2+ in aqueous solution by direct action of molecular nitrogen. J Am Chem Soc. 89:5706.
Books, Book Chapters and Reviews:
Ertl RP, Harrison DE. 200_. Dietary restriction: A model system probing the cell fate decision between cancer and senescence. In: Mouse models of human blood cancers — basic research and pre-clinical applications. Li S, (ed). Springer (in press).
Flurkey K, Currer JM, Harrison DE. 2007. The mouse in aging research. In: The Mouse in Biomedical Research, 2nd Edition, Vol III, Normative Biology, Husbandry, and Models. Fox JG et al, (eds). American College of Laboratory Animal Medicine (Elsevier), Burlington, MA. pp. 637-672.
Harrison DE, Chen J, Astle CM. 2001. Repopulating patterns of primitive hematopoietic stem cells. In: Stem Cell Biology. Marshak D, et al editors. Chapter 6, pp. 111-127, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
Harrison DE. 1995. Book review of The SAM Model of Senescence, Takeda T (ed). Exp Gerontol. 30:545-8.
Harrison DE. 1993. Competitive repopulation in unirradiated normal recipients. Blood. 81:2473-2474.
Harrison DE. 1992. Difficulties with studying accelerated aging. Growth Dev Aging. 56:67 (editorial).
Harrison DE. 1992. Evaluating functional abilities of primitive hemopoietic stem cells. In: Stem Cells in Hematopoiesis: Animal Models and Human Transplantation, Muller-Sieburg C et al (eds), Springer-Verlag, Curr Top Microbiol Immunol 177:13-30.
Harrison DE, Archer JR, Kent B. 1991. Genes regulate effects of dietary restriction. In: Biological Effects of Dietary Restriction, Fishbein L (ed), Springer-Verlag, pp. 264-86.
Flurkey K, Harrison DE. 1990. Use of genetic models to investigate the hypophyseal regulation of senescence. In: Genetic Effects on Aging II, Harrison DE (ed), Caldwell, NJ, Telford Press, pp. 437-56.
Harrison DE, Archer JR. 1990. Genotype modulates the effects of caloric restriction on aging processes in rodents. In: The Potential for Nutritional Modulation of the Aging Processes, Ingram et al (eds), Trumbell, CT, Food and Nutrition Press, Inc., pp. 137-56.
Miller RA, Harrison DE. 1987. A clonal analysis of age-associated changes in T-cell reactivity. In: Aging and the Immune Response, Chapter 1, Goidl EA (ed.), New York, Marcel Dekker, Inc., pp. 1-26.
Harrison DE. 1985. Cell and tissue transplantation: a means of studying the aging process. In: Handbook of the Biology of Aging, Chapter 13, Finch CE, Schneider E (eds), New York, Van Nostrand & Reinhold Co., pp. 322-56.
Harrison DE, Archer JR, Astle CM. 1983. Use of the mouse in bioassays for aging. In: Intervention in the Aging Process, Part B, Basic Research and Preclinical Screening, Regelson W, Sinex FM (eds), New York, A.R. Liss, Inc., pp. 359-75.
Harrison DE. 1982. Experience with developing assays of physiological age. In: Biological Markers of Aging, Reff ME, Schneider EL (eds), NIH Publ. No. 82-2221, pp. 2-12.
Harrison DE. 1982. The nature of aging. In: Psychopharmacology Of Old Age, Wheatley D (ed), England, Oxford Univ. Press, pp. 3-14.
Harrison DE. 1981. Immunohemopoietic stem cell lines. In: Biological Mechanisms in Aging Conference, June 23-25, 1980, Schimke RT (ed), NIH Publ. No. 81-2194, pp. 505-16.
Harrison DE. 1981. Immunopoietic stem cell lines: effects of aging and transplantation. In: Immunological Aspects of Aging, Serge D, Smith L (eds), Marcel Dekker, Inc, New York, pp. 43-56.
Harrison DE. 1981. Measuring the functional abilities of stem cell lines. In: Immunological Techniques Applied to Aging Research, Adler WH, Nordin AA (eds), UniScience, Florida, CRC Press, pp. 37-50.
Harrison DE. 1979. Use of genetic anemias in mice as tools for hematological research, In: Cellular Dynamics of Hemaopoiesis, Vol. 8, No. 2. Clinics in Haematology, Lajtha LG (ed), W R Saunders, London, pp. 239-62.
Harrison DE, Mobraaten LE. 1979. Marrow allograft survival in W/Wv anemic mice: effects on skin graft survival and effects of preimmunization. In: Experimental Hematology Today, Baum SJ, Ledney GD (eds), New York, Springer-Verlag, pp. 233-38.
Harrison DE. 1978. Is limited cell proliferation the clock that times aging? In: The Biology of Aging, Behnke JA, Finch CE, Moment GB (eds), New York, Plenum Publishing Corp., pp. 33-55.
Page last updated September 5, 2008.