Alzheimer's Disease Mouse Model Resource
The Jackson Laboratory offers a variety of genetic models for Alzheimer's disease (AD) research. AD models are made congenic on inbred strains, usually C57BL/6J, to stabilize the genetic background. Numerous novel strains carrying alleles of genes that have been identified as potential targets for AD therapies or AD risk genes by GWAS have been identified and imported for distribution.
Learn about our JAX® Mice and other resources to support biomedical research:
- JAX® Mice for Alzheimer's Disease Research
- Alzheimer's Disease Mouse Model List (.pdf)
- Neurobiology Resource Manual (request form)
Comparison of Alzheimer's disease models
This table summarizes the differences between important mouse models for Alzheimer's disease research.
Important resources for Alzheimer's disease research
The Jackson Laboratory has appointed a special research administrator for Alzheimer's disease (AD) to enhance the distribution of mouse models from the Alzheimer's Disease Mouse Model Resource (ADMMR). Dr. Michael Sasner will serve as a resource for scientists seeking information about existing models, and also oversee the selection, importation, and distribution of new AD models.
Dr. Sasner, who has a Ph.D. in Neuroscience from the University of Connecticut, has been at The Jackson Laboratory since 1998. Scientists with questions or information about potential new strains for distribution can reach Dr. Sasner at mike.sasner@jax.org.
