Alzheimer's Disease Mouse Model Resource

The Jackson Laboratory offers a variety of genetic models for Alzheimer's disease (AD) research. AD models are made congenic on inbred strains, usually C57BL/6J, to stabilize the genetic background. Numerous novel strains carrying alleles of genes that have been identified as potential targets for AD therapies or AD risk genes by GWAS have been identified and imported for distribution.

Learn about our JAX® Mice and other resources to support biomedical research:

Comparison of Alzheimer's disease models

This table summarizes the differences between important mouse models for Alzheimer's disease research.