Scientists uncover essential role of postsynaptic NMDA receptors in developmental refinement of excitatory synapses.
Understanding the organization and functional compartmentalization of the genome is important to future disease studies.
National ALS mouse model resource is a key component in the effort to uncover the root causes of Lou Gehrig's Disease.
Team led by Zhong-wei Zhang, Ph.D., has discovered a factor in synapse-building, also showing that the building and pruning processes occur independent of each other.
The collaboration seeks to identify biomarkers, molecules that provide targets for candidate drugs and help predict when they will be most effective.
SMA has been traced to mutations in the motor neuron (SMN1) gene that reduce levels of a protein known as SMN.