Why mouse genetics?

The laboratory mouse is a powerful system for mammalian genetic and biomedical research. The physiology shared between mice and humans makes the mouse ideal for modeling complex human diseases and for drug efficacy testing. Mice provide effective models for diseases and conditions such as atherosclerosis, hypertension, diabetes, osteoporosis, glaucoma, neurological and neuromuscular disorders, and cancer, as well as many rare diseases.

Advantages of the mouse as a model organism

  • Genetic manipulation of the mouse genome
  • Identification of causative mutations in the mouse genome
  • Characterization of genetic background effects
  • Value of inbred strains and strain panels

Development of the laboratory mouse

  • Early history
  • The progress of mouse genetics
  • The mouse in biomedical research

Resources for researchers

In addition to providing our premier mouse models, The Jackson Laboratory offers a wealth of expertise, technical information and resources to support researchers.