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Genetic Resource Science (GRS) initiates and develops resource-generating research. Our team:
We supply the scientific community with the most comprehensive collection of mouse genetic resources and mouse-related technologies, such as ES cells and tool strains. Our work strengthens and diversifies the resources available for basic, biomedical and preclinical research.
GRS offers support for scientists already using mice and those just starting to explore how a mouse model could enhance the progress of their discoveries.
To develop new research resources, GRS scientists conduct hypothesis-driven research in their individual areas of interest. We also adapt technologies to enhance them for use in our own research or that of other scientists.
Our team has a broad base of experience, enabling us to take on projects that require a variety of expertise. We can partner directly with other scientists to help them resolve research issues that require special strains, resources or tools.
Our Repository maintains more than 1,800 strains live as breeding colonies for rapid distribution and over 6,000 others as cryopreserved stock or DNA for dissemination to the worldwide scientific community. We are experts at genetic background stabilization, and we maintain the highest standards of quality control. Every strain has an allele-specific genotyping assay, and breeders and offspring are genotyped when a clinical phenotype isn't apparent. Data sheets for each strain document performance, husbandry, genotype, phenotype and more.
Our research and development programs add many new models to the Repository each year and enhance the value of available strains.
Genetic Resource Science (GRS) initiates and develops resource-generating research. Our team:
We supply the scientific community with the most comprehensive collection of mouse genetic resources and mouse-related technologies, such as ES cells and tool strains. Our work strengthens and diversifies the resources available for basic, biomedical and preclinical research.
GRS offers support for scientists already using mice and those just starting to explore how a mouse model could enhance the progress of their discoveries.
To develop new research resources, GRS scientists conduct hypothesis-driven research in their individual areas of interest. We also adapt technologies to enhance them for use in our own research or that of other scientists.
Our team has a broad base of experience, enabling us to take on projects that require a variety of expertise. We can partner directly with other scientists to help them resolve research issues that require special strains, resources or tools.
Our Repository maintains more than 1,800 strains live as breeding colonies for rapid distribution and over 6,000 others as cryopreserved stock or DNA for dissemination to the worldwide scientific community. We are experts at genetic background stabilization, and we maintain the highest standards of quality control. Every strain has an allele-specific genotyping assay, and breeders and offspring are genotyped when a clinical phenotype isn't apparent. Data sheets for each strain document performance, husbandry, genotype, phenotype and more.
Our research and development programs add many new models to the Repository each year and enhance the value of available strains.
We work closely with foundations, biotech firms and pharmaceutical companies to develop new models and further translational research.
We develop models for basic research, tools for exploring disease mechanisms on a molecular level and precision models of human disease.
How working with genetically diverse could revolutionize our understanding of human disease and treatment.
Diverse mouse models show promise in how we understand and treat diseases, offering a significant improvement over standardized but limited mouse and cellular models.
Mice don’t get Alzheimer’s—and while that’s good news for mice, it’s a big problem for biomedical researchers seeking to understand the disease and test new treatments. Now, researchers at The Jackson Laboratory are working to create the first strain of mice that’s genetically susceptible to late-onset Alzheimer’s, with potentially transformative implications for dementia research.
Genetic testing is a powerful tool in the fight against cancer, playing a crucial role in both prevention and personalized treatment. But what exactly are the different types of genetic tests, and how do they help?
Explore five research tools and methods that didn't exist ten years ago that could be medical game changers.
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Reenergizing exhausted T cells, with help from a rare immune cell known as a basophil, can kickstart the immune system into fighting cancer.
Dan Cortes multifaceted journey has led him to pioneering stem cell research within the Pera lab, where he explores the intricate genetic landscape underlying neurological diseases and disorders.